Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

4.1.1.29

Official Name

sulfinoalanine decarboxylase

Name from literature

sulfoalanine decarboxylase

Pathway from literature

taurine biosynthesis

Pathway from KEGG

Metabolism of Other Amino Acids; Taurine and hypotaurine metabolism; map00430

Organisms

Human (9606)

Genome localization

12q13.11-q14.3[51380 ],

Comments

A pyridoxal-phosphate protein. Also acts on L-cysteate. The 1992 edition of the Enzyme List erroneously gave the name sulfoalanine decarboxylase to this enzyme.

Rate-limiting Description

"Cysteine sulfinic acid decarboxylase (CSD) is the rate-limiting enzyme for biosynthesis of taurine which is essential to biological processes such as development of the brain and eye, reproduction, osmoregulation as well as the anti-inflammatory activity of leukocytes." (11997111)

"Cysteine sulfinic acid decarboxylase, a rate-limiting enzyme for taurine biosynthesis, has been cloned and sequenced in the mouse, rat and human." (14553911)

Regulatory Information

Regulatory type

Detail

phosphorylation;

Q9Y600

Gene ontology

Gene ontology

GO:0004782 (F) sulfinoalanine decarboxylase activity [Q9Y600 ];
GO:0030170 (F) pyridoxal phosphate binding [Q9Y600 ];
GO:0019752 (P) carboxylic acid metabolic process [Q9Y600 ];

Links

SwissProt

Q9Y600

Entrez Gene

51380

HPRD

16763



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  Last Modified: 2009-03-24  
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