Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

Official Name

Name from literature

Pathway from literature

Organisms

()

Rate-limiting Description

"." ()

Regulatory Information

Upstream transcription factor

7157;3091

Regulatory type

Detail

key enzyme;

"They lower intraocular pressure by inhibiting carbonic anhydrase, a key enzyme for aqueous humor formation." (11224713)

phosphorylation;

"a novel phosphorylation-regulated carbonic anhydrase II binding site exists in distal amino acids of the Na+/H+ exchanger tail." (16475831)

transcriptional factor;"p53(7157),HIF-1alpha(3091)"

"upon activation by DNA damage, wt p53 mediates an accelerated degradation of HIF-1alpha protein, resulting in reduced activation of CA9 transcription and, correspondingly, decreased levels of CA9 protein" (15199132)

transcriptional factor;HIF-1alpha(3091)

"high levels of the hypoxia regulated proteins HIF1alpha and CA9 in HNC predict resistance to platinum based radio-chemotherapy." (17852557)

phosphorylation;

O43570

phosphorylation;

P00918

phosphorylation;

Q16790

phosphorylation;

Q9ULX7

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  Last Modified: 2009-03-24  
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