Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

2.1.1.79

Official Name

cyclopropane-fatty-acyl-phospholipid synthase

Name from literature

cyclopropane fatty acid synthase

Pathway from literature

formation of cyclopropane rings on unsaturated fatty acids

Organisms

E.coli (83333)

Genome localization

-[944811 ],

Comments

The enzyme adds a methylene group across the 9,10 position of a Delta9-olefinic acyl chain in phosphatidylethanolamine or, more slowly, phosphatidylglycerol or phosphatidylinositol, forming a cyclopropane derivative (cf. EC 2.1.1.16 methylene-fatty-acyl-phospholipid synthase).

Rate-limiting Description

"Isotope and elemental effects indicate a rate-limiting methyl transfer as the initial step in the reaction catalyzed by Escherichia coli cyclopropane fatty acid synthase." (15491158)

Gene ontology

Gene ontology

GO:0008610 (P) lipid biosynthetic process [P0A9H7 ];
GO:0008825 (F) cyclopropane-fatty-acyl-phospholipid syntha... [P0A9H7 ];
GO:0005737 (C) cytoplasm [P0A9H7 ];
GO:0005515 (F) protein binding [P0A9H7 ];

Subcellular localization

Localization

cytoplasm [P0A9H7 ];

Links

SwissProt

P0A9H7

Entrez Gene

944811



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  Last Modified: 2009-03-24  
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