Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

1.3.1.9

Official Name

enoyl-[acyl-carrier-protein] reductase (NADH)

Name from literature

enoyl ACP reductase

Pathway from literature

the elongation of unsaturated fatty acids

Pathway from KEGG

Lipid Metabolism; Fatty acid biosynthesis; map00061

Organisms

E.coli (83333)

Genome localization

-[945870 ],

Comments

Catalyses the reduction of enoyl-acyl-[acyl-carrier-protein] derivatives of carbon chain length from 4 to 16.

Rate-limiting Description

"Among them, FabI is an enoyl-ACP reductase which catalyzes the final and rate-limiting step of bacterial FAS." (17095231)

"coli strains with the hybrid FAS system unexpectedly revealed that enoyl-ACP reductase catalyses a rate-limiting step in the elongation of unsaturated fatty acids." (8075395)

Gene ontology

Gene ontology

GO:0046677 (P) response to antibiotic [P0AEK4 ];
GO:0005739 (C) mitochondrion [P0AEK4 ];
GO:0005886 (C) plasma membrane [P0AEK4 ];
GO:0004318 (F) enoyl- [acyl-carrier-protein] reductase (NAD... [P0AEK4 ];
GO:0055114 (P) oxidation reduction [P0AEK4 ];
GO:0005515 (F) protein binding [P0AEK4 ];
GO:0006633 (P) fatty acid biosynthetic process [P0AEK4 ];

Subcellular localization

Localization

cell membrane [P0AEK4 ];

Links

SwissProt

P0AEK4

Entrez Gene

945870



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  Last Modified: 2009-03-24  
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