Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

Official Name

glutathione synthase

Name from literature

Glutathione synthase

Pathway from literature

biosynthesis of glutathione and phytochelatins

Pathway from KEGG

Metabolism of Other Amino Acids; Glutathione metabolism; map00480

Amino Acid Metabolism; Glutamate metabolism; map00251


E.coli (83333)

Genome localization

-[947445 ],

Rate-limiting Description

"We conclude that in the presence of Cd, the GS enzyme is rate limiting for the biosynthesis of glutathione and phytochelatins, and that overexpression of GS offers a promising strategy for the production of plants with superior heavy-metal phytoremediation capacity." (9880348)

Gene ontology

Gene ontology

GO:0030145 (F) manganese ion binding [P04425 ];
GO:0004363 (F) glutathione synthase activity [P04425 ];
GO:0000287 (F) magnesium ion binding [P04425 ];
GO:0006750 (P) glutathione biosynthetic process [P04425 ];
GO:0005829 (C) cytosol [P04425 ];
GO:0005515 (F) protein binding [P04425 ];
GO:0005524 (F) ATP binding [P04425 ];




Entrez Gene


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  Last Modified: 2009-03-24  
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