Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

6.3.2.3

Official Name

glutathione synthase

Name from literature

Glutathione synthase

Pathway from literature

biosynthesis of glutathione and phytochelatins

Pathway from KEGG

Metabolism of Other Amino Acids; Glutathione metabolism; map00480

Amino Acid Metabolism; Glutamate metabolism; map00251

Organisms

E.coli (83333)

Genome localization

-[947445 ],

Rate-limiting Description

"We conclude that in the presence of Cd, the GS enzyme is rate limiting for the biosynthesis of glutathione and phytochelatins, and that overexpression of GS offers a promising strategy for the production of plants with superior heavy-metal phytoremediation capacity." (9880348)

Gene ontology

Gene ontology

GO:0030145 (F) manganese ion binding [P04425 ];
GO:0004363 (F) glutathione synthase activity [P04425 ];
GO:0000287 (F) magnesium ion binding [P04425 ];
GO:0006750 (P) glutathione biosynthetic process [P04425 ];
GO:0005829 (C) cytosol [P04425 ];
GO:0005515 (F) protein binding [P04425 ];
GO:0005524 (F) ATP binding [P04425 ];

Links

SwissProt

P04425

Entrez Gene

947445



  Copyright 2009, Center for Bioinformatics 
  Last Modified: 2009-03-24  
  Design by Zhao Min