Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

2.7.1.33

Official Name

pantothenate kinase

Name from literature

pantothenate kinase

Pathway from literature

coenzyme A ( CoA ) biosynthetic pathway

Pathway from KEGG

Metabolism of Cofactors and Vitamins; Pantothenate and CoA biosynthesis; map00770

Organisms

Yeast (4932)

Genome localization

-[852144 ],

Rate-limiting Description

"The acetyl-CoA levels also increased ( approximately 5-fold) but not as much as that of CoA, showing that the carbon flux from the pyruvate node is rate-limiting upon an increase in CoA levels." (15176870)

"Fms1 is a rate-limiting enzyme for the biosynthesis of pantothenic acid in yeast." (15843025)

Gene ontology

Gene ontology

GO:0005634 (C) nucleus [Q04430 ];
GO:0004594 (F) pantothenate kinase activity [Q04430 ];
GO:0015937 (P) coenzyme A biosynthetic process [Q04430 ];
GO:0005737 (C) cytoplasm [Q04430 ];
GO:0005515 (F) protein binding [Q04430 ];
GO:0005524 (F) ATP binding [Q04430 ];

Subcellular localization

Localization

nucleus [Q04430 ];

cytoplasm [Q04430 ];

Links

SwissProt

Q04430

Entrez Gene

852144



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  Last Modified: 2009-03-24  
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