Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

4.1.1.17

Official Name

ornithine decarboxylase

Name from literature

ornithine decarboxylase

Pathway from literature

polyamine metabolism

Pathway from KEGG

Metabolism of Other Amino Acids; Glutathione metabolism; map00480

Amino Acid Metabolism; Urea cycle and metabolism of amino groups; map00220

Organisms

Yeast (4932)

Genome localization

-[853651 ],

Comments

A pyridoxal-phosphate protein.

Rate-limiting Description

"Ornithine decarboxylase (ODC), the first rate-limiting enzyme in the polyamine biosynthesis is one of the most rapidly degraded proteins in eukaryotic cells." (12054575)

Regulatory Information

Upstream transcription factor

853167;854465

Regulatory type

Detail

transcriptional factor;GCN5(853167)

"Functional interaction between GCN5 and polyamines: a new role for core histone acetylation." (10523306)

transcriptional factor;SNF2(854465)

"Functional interaction between GCN5 and polyamines: a new role for core histone acetylation." (10523306)

Gene ontology

Gene ontology

GO:0015940 (P) pantothenate biosynthetic process [P08432 ];
GO:0009446 (P) putrescine biosynthetic process [P08432 ];
GO:0004586 (F) ornithine decarboxylase activity [P08432 ];
GO:0005737 (C) cytoplasm [P08432 ];

Links

SwissProt

P08432

Entrez Gene

853651



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  Last Modified: 2009-03-24  
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