Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

2.7.1.48

Official Name

uridine kinase

Name from literature

Uridine-cytidine nucleoside kinase

Pathway from literature

pyrimidine-nucleotide salvage pathway

Pathway from KEGG

Xenobiotics Biodegradation and Metabolism; Drug metabolism - other enzymes; map00983

Nucleotide Metabolism; Pyrimidine metabolism; map00240

Organisms

Rat (10116)

Comments

Cytidine can act as acceptor; GTP and ITP can act as donors.

Rate-limiting Description

"The activity of uridine kinase (ATP: uridine 5'-phosphotransferase; EC 2.7.1.48), the rate-limiting enzyme of the UMP salvage pathway, was measured in human ovaries and ovarian carcinomas, in a spectrum of six rat hepatomas of different growth rates and in eleven normal rat tissues of high and low cell renewal rates." (9923963)

Gene ontology

Gene ontology

GO:0016773 (F) phosphotransferase activity, alcohol group ... [Q9QYG8 ];
GO:0004849 (F) uridine kinase activity [Q9QYG8 ];
GO:0008152 (P) metabolic process [Q9QYG8 ];
GO:0005524 (F) ATP binding [Q9QYG8 ];

Links

SwissProt

Q9QYG8



  Copyright 2009, Center for Bioinformatics 
  Last Modified: 2009-03-24  
  Design by Zhao Min