|
||||
|
||||
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases |
Basic Information |
|
---|---|
Enzyme Number | 2.7.1.91 |
Official Name | sphinganine kinase |
Name from literature | sphingosine kinase |
Pathway from literature | synthesis of sphingosine 1-phosphate |
Pathway from KEGG |
Lipid Metabolism; Sphingolipid metabolism; map00600 |
Environmental Information Processing; Signal Transduction; Calcium signaling pathway; map04020 | |
Environmental Information Processing; Signal Transduction; VEGF signaling pathway; map04370 | |
Organisms | Mouse (10090) |
Genome localization | |
Rate-limiting Description | "BACKGROUND: Phosphorylation of sphingosine by sphingosine kinase (SK) is the rate-limiting step in the cellular synthesis of sphingosine 1-phosphate (S1P)." (15451787) |
Regulatory Information |
|
Regulatory type | Detail |
phosphorylation; | Q8CI15:from_uniprot:193_Phosphothreonine |
phosphorylation; | Q9JIA7:from_uniprot:364_Phosphoserine |
Gene ontology |
|
Gene ontology |
GO:0005624 (C) membrane fraction [Q9JIA7 ]; |
Links |
|
SwissProt | |
Entrez Gene |
Copyright 2009, Center for Bioinformatics | |||
Last Modified: 2009-03-24 | |||
Design by Zhao Min |