Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

Official Name

carbamoyl-phosphate synthase (ammonia)

Name from literature

carbamyl phosphate synthetase I

Pathway from literature

urea cycle/urea production

Pathway from KEGG

Amino Acid Metabolism; Urea cycle and metabolism of amino groups; map00220

Amino Acid Metabolism; Glutamate metabolism; map00251

Amino Acid Metabolism; Arginine and proline metabolism; map00330

Energy Metabolism; Nitrogen metabolism; map00910


Mouse (10090)

Genome localization

1 C3|1 43.4 cM[227231 ],

Rate-limiting Description

"Determinations of specific activities of the other enzymes in this pathway reveal that the activity of carbamyl phosphate synthetase II, the rate-limiting step, is elevated 2- to 3-fold in both resistant lines." (7459875)

Gene ontology

Gene ontology

GO:0006541 (P) glutamine metabolic process [Q8C196 ];
GO:0005739 (C) mitochondrion [Q8C196 ];
GO:0000050 (P) urea cycle [Q8C196 ];
GO:0004087 (F) carbamoyl-phosphate synthase (ammonia) acti... [Q8C196 ];
GO:0005524 (F) ATP binding [Q8C196 ];

Subcellular localization


mitochondrion [Q8C196 ];




Entrez Gene


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  Last Modified: 2009-03-24  
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