Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

Official Name

methylenetetrahydrofolate dehydrogenase (NAD+)

Name from literature

tetrahydrofolate dehydrogenase

Pathway from literature

metabolism of folate

Pathway from KEGG

Metabolism of Cofactors and Vitamins; One carbon pool by folate; map00670


Rat (10116)

Genome localization

5q33[313410 ],

Rate-limiting Description

"The activity of tetrahydrofolate dehydrogenase, the first and rate-limiting enzyme in the metabolism of folate, was increased in the folate supplemented rats (group C) and reduced in the rats given a folic acid-free diet (group A)." (718836)


Entrez Gene


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  Last Modified: 2009-03-24  
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