Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

2.6.1.13

Official Name

ornithine aminotransferase

Name from literature

ornithine delta aminotransferase

Pathway from literature

synthesis of transmitter glutamate and gamma-aminobutyric acid ( GABA )

Pathway from KEGG

Amino Acid Metabolism; Arginine and proline metabolism; map00330

Organisms

Mouse (10090)

Genome localization

7 F3|7 63.0 cM[18242 ],

Comments

A pyridoxal-phosphate protein.

Rate-limiting Description

"The specific activity of only ornithine aminotransferase (OAT), the rate-limiting enzyme in the conversion of ornithine to proline, increased in 2 weeks of hypertrophy." (11691635)

Gene ontology

Gene ontology

GO:0030170 (F) pyridoxal phosphate binding [P29758 ];
GO:0005759 (C) mitochondrial matrix [P29758 ];
GO:0004587 (F) ornithine-oxo-acid transaminase activity [P29758 ];

Subcellular localization

Localization

mitochondrion [P29758 ];

Links

SwissProt

P29758

Entrez Gene

18242



  Copyright 2009, Center for Bioinformatics 
  Last Modified: 2009-03-24  
  Design by Zhao Min