Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

2.5.1.16

Official Name

spermidine synthase

Name from literature

spermidine synthase

Pathway from literature

formation of the spermine precursor spermidine from putrescine

Pathway from KEGG

Metabolism of Other Amino Acids; Glutathione metabolism; map00480

Amino Acid Metabolism; Urea cycle and metabolism of amino groups; map00220

Metabolism of Other Amino Acids; beta-Alanine metabolism; map00410

Amino Acid Metabolism; Methionine metabolism; map00271

Organisms

Mouse (10090)

Genome localization

4 E2[20810 ],

Comments

This enzyme is not identical with EC 2.5.1.22, spermine synthase. The mammalian enzyme is highly specific but the bacterial enzyme can use other acceptors and can synthesize spermine.

Rate-limiting Description

"They are synthesized by a set of specific enzymes in which spermidine synthase is the rate-limiting step catalysing the formation of the spermine precursor spermidine from putrescine." (16515550)

Gene ontology

Gene ontology

GO:0008295 (P) spermidine biosynthetic process [Q64674 ];
GO:0004766 (F) spermidine synthase activity [Q64674 ];

Links

SwissProt

Q64674

Entrez Gene

20810



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  Last Modified: 2009-03-24  
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