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Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases |
Basic Information |
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Enzyme Number | 2.3.1.20 |
Official Name | diacylglycerol O-acyltransferase |
Name from literature | diacylglycerol acyltransferase |
Pathway from literature | diacylglycerol conversion to triacylglycerol |
Pathway from KEGG |
Lipid Metabolism; Glycerolipid metabolism; map00561 |
Metabolism of Cofactors and Vitamins; Retinol metabolism; map00830 | |
Organisms | Mouse (10090) |
Genome localization | |
Comments | Palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. |
Rate-limiting Description | "Acyl-CoA:monoacylglycerol acyltransferase (MGAT) plays an important role in dietary fat absorption by catalyzing a rate-limiting step in the re-synthesis of diacylglycerols in enterocytes." (12730219) |
Regulatory Information |
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Upstream transcription factor | |
Regulatory type | Detail |
phosphorylation; | Q9Z2A7:from_uniprot:20_Phosphoserine |
transcriptional factor;"C/EBPbeta(12608),C/EBPalpha(12606)" | "diacylglycerol acyltransferase 2 expression is regulated by CAAT/enhancer-binding protein beta (C/EBPbeta) and C/EBPalpha during adipogenesis" (17504763) |
Gene ontology |
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Gene ontology |
GO:0006071 (P) glycerol metabolic process [Q9DCV3 ]; |
Subcellular localization |
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Localization | |
Links |
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SwissProt | |
Entrez Gene |
Copyright 2009, Center for Bioinformatics | |||
Last Modified: 2009-03-24 | |||
Design by Zhao Min |