Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

1.1.99.5

Official Name

glycerol-3-phosphate dehydrogenase

Name from literature

glycerol phosphate dehydrogenase

Pathway from literature

glycerol phosphate shuttle

Pathway from KEGG

Lipid Metabolism; Glycerophospholipid metabolism; map00564

Organisms

Rat (10116)

Genome localization

3q21-q23[25062 ],

Rate-limiting Description

"Mitochondrial FAD-linked glycerophosphate dehydrogenase (m-GDH) catalyzes a rate-limiting step of the glycerol phosphate shuttle in pancreatic islets." (8621016)

"It catalyses a rate-limiting step of the glycerol phosphate shuttle in pancreatic islets." (8329724)

Regulatory Information

Regulatory type

Detail

phosphorylation;

P35571

phosphorylation;

P35571:from_uniprot:600_Phosphotyrosine

phosphorylation;

P35571:from_uniprot:601_Phosphotyrosine

Gene ontology

Gene ontology

GO:0006072 (P) glycerol-3-phosphate metabolic process [P35571 ];
GO:0004368 (F) glycerol-3-phosphate dehydrogenase activity [P35571, Q6LCP5 ];
GO:0009331 (C) glycerol-3-phosphate dehydrogenase complex [P35571 ];
GO:0005739 (C) mitochondrion [P35571 ];
GO:0055114 (P) oxidation reduction [P35571, Q6LCP5 ];
GO:0005509 (F) calcium ion binding [P35571 ];

Subcellular localization

Localization

mitochondrion [P35571 ];

Links

SwissProt

P35571; Q6LCP5

Entrez Gene

25062



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  Last Modified: 2009-03-24  
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