Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

2.7.7.14

Official Name

ethanolamine-phosphate cytidylyltransferase

Name from literature

phosphoethanolamine cytidylyltransferase

Pathway from literature

phosphatidylethanolamine synthesis

Pathway from KEGG

Metabolism of Other Amino Acids; Aminophosphonate metabolism; map00440

Lipid Metabolism; Glycerophospholipid metabolism; map00564

Organisms

Mouse (10090)

Genome localization

11 E2[68671 ],

Rate-limiting Description

"Proposed iPLA2beta functions include participation in phosphatidylcholine (PC) homeostasis by degrading excess PC generated in CHO cells that overexpress CTP:phosphocholine cytidylyltransferase (CT), which catalyzes the rate-limiting step in PC biosynthesis; participation in biosynthesis of arachidonate-containing PC species in P388D1 cells by generating lysophosphatidylcholine (LPC) acceptors for arachidonate incorporation; and participation in signaling events in insulin secretion from islet beta-cells." (11521967)

Gene ontology

Gene ontology

GO:0004306 (F) ethanolamine-phosphate cytidylyltransferase... [Q922E4 ];
GO:0008654 (P) phospholipid biosynthetic process [Q922E4 ];

Links

SwissProt

Q922E4

Entrez Gene

68671



  Copyright 2009, Center for Bioinformatics 
  Last Modified: 2009-03-24  
  Design by Zhao Min