Center for Bioinformatics
Oxidoreductases | Transferases | Hydrolases | Lyases | Isomerases | Ligases

Basic Information

Enzyme Number

1.1.1.21

Official Name

aldehyde reductase

Name from literature

aldose reductase

Pathway from literature

the polyol pathway

Pathway from KEGG

Lipid Metabolism; Glycerolipid metabolism; map00561

Carbohydrate Metabolism; Pyruvate metabolism; map00620

Carbohydrate Metabolism; Fructose and mannose metabolism; map00051

Carbohydrate Metabolism; Pentose and glucuronate interconversions; map00040

Carbohydrate Metabolism; Galactose metabolism; map00052

Organisms

Mouse (10090)

Genome localization

6 B1|6 14.0 cM[11997 ], 6 B1|6 13.0 cM[14187 ], 6 B1|6 13.0 cM[11677 ],

Comments

Has wide specificity.

Rate-limiting Description

"." ()

Regulatory Information

Regulatory type

Detail

phosphorylation;

P45376:from_uniprot:23_Phosphoserine

;

P45376:from_uniprot:40_Phosphotyrosine

Gene ontology

Gene ontology

GO:0044255 (P) cellular lipid metabolic process [P21300 ];
GO:0055114 (P) oxidation reduction [P45377, P45376, P21300 ];
GO:0005737 (C) cytoplasm [P45377, P45376, P21300 ];
GO:0004032 (F) aldehyde reductase activity [P45377, P45376, P21300 ];

Subcellular localization

Localization

cytoplasm [P45377, P45376, P21300 ];

Links

SwissProt

P21300; P45376; P45377

Entrez Gene

11677; 11997; 14187



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  Last Modified: 2009-03-24  
  Design by Zhao Min